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The seismic amplification factor Cd can be input for each direction independently. It is recommended to use the default values fromult from ASCE 7 - Table 12.2-1 unless there are exceptional circumstances.
For bearing wall systems: Wood panels - 4 Other materials - 2.0
For building frame systems : Wood panels - 4.5 Other materials - 2.5
These are summarized for each material in Shearwalls in Seismic Provisions.
The seismic amplification factor is used in the calculation of story drift in 12.8.6, equation 12.8-15.